Found right across from the Guggenheim, this hotel occupies a prime position. Opened in 2002, it was considered the first to have been fully ‘made in Spain’. Designed by Javier Mariscal, it’s colourful and ultra-modern, presenting an impressive art collection. In addition to its overnight guests, it welcomes those wishing to frequent the Gran Hotel Domine’s impressive roof terrace. The 145 rooms here are both soundproofed and air-conditioned, spread across its seven floors. Plus there’s a sleek spa and health club, lobby bar, cafe and restaurant – all complimenting the cutting edge contemporary aesthetic that runs throughout the building.