Best Luxury 5 Star Hotels in Lazio

Discover our favourite luxury accommodation in Lazio. Our collection of luxury hotels and resorts showcase the very finest in world-class hospitality. Each one has been selected, by our Editors, based on its exceptional service, refined interiors, excellent amenities and standout location. Let our expert selection help you find your perfect place to stay.

Lazio, Rome, Trevi

Maalot Roma

Hotel
(5 stars)
At a glance
Rooms 30 individually Designed Rooms & Suites with Bespoke Furnishings & Marble Bathrooms
Amenities Don Pasquale Restaurant & Bar offering Modern Roman Cuisine & a Private Fitness Area with Technogym Equipment
More Located Steps from the Trevi Fountain & Via Condotti in a Historic Palazzo with Eclectic interiors

Those avoiding chain hotel brands will love this unique boutique gem and its personalised white-glove service. It’s found in a romantic Roman palazzo and was once home to the opera composer Gaetano Donizetti. Evoking a sense of drama and theatre, it has been lovingly restored to fuse its grander period aspects with a colourful contemporary style. Each room and suite is a work of art, containing curated furnishings and details. Maalot Rona’s Don Pasquale Restaurant & Bar (named after Donizetti’s famed 19th-century opera) is set in agarden, with food by Executive Chef Domenico Boschi. Although close to A-list sights like the Trevi Fountain and the Via Condotti shopping district this beautiful boutique hotel is a haven in the bustling city.

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Lazio, Rome

art’otel Rome Piazza Sallustio

Hotel
(5 stars)
At a glance
Rooms 99 Including Suites with Private Terraces
Amenities Yezi Pan-Asian Restaurant & Terrace, Art Gallery, Cultural Events (Art’beat), Curated Interiors by Pietro Ruffo
More Immersive Artist-led Design, Dynamic Art Programming, Central Location near Horti Sallustiani

art’otel Rome Piazza Sallustio brings a bold, culturally immersive experience to the heart of Rome. Set just steps from the Horti Sallustiani, this contemporary lifestyle hotel comprising 99 stylish rooms, offers guests more than just a stay—it’s a living gallery, with each space enriched by the imaginative works of Signature Artist Pietro Ruffo. His celestial-inspired pieces and Roman iconography feature throughout, creating a striking artistic narrative from lobby to suite.

At the centre of the hotel’s cultural focus is its Art Gallery, which opens with Ruffo’s exhibition Mappare l’Invisibile and forms part of the wider art’beat initiative. This evolving programme brings together visual art, music, fashion, and wellness, offering guests and locals a curated calendar of creative experiences. Culinary artistry also takes centre stage at YEZI, a pan-Asian restaurant led by Executive Chef Werner Seebach and Head Chef Giordano Gianforchetti. With a menu inspired by Asia’s spice routes and a terrace designed by Ruffo himself, YEZI delivers one of the capital’s most imaginative dining experiences.

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Lazio, Rome, Pantheon

Palazzo Roma

Hotel
(5 stars)
At a glance
Rooms 39 Rooms Including 22 Suites Offer Individually Designed Spaces With High Ceilings & Marble Bathrooms.
Amenities Facilities Include A Refined Restaurant Serving Roman Cuisine, A Stylish Bar, In-Room Spa Treatments & Access To A Nearby Gym.
More Located On Via Del Corso, The Hotel Is Within Walking Distance Of The Trevi Fountain, Spanish Steps & Pantheon.

With an enviable address of Via del Corso, Palazzo Roma, is a historic 16th-century building that has been transformed into a luxurious hotel that fuses modern elegance and historical richness. Once the residence of various noble Tuscan families, this esteemed Roman heritage site now serves as a boutique hotel set across three floors. Its design celebrates the building’s aristocratic past with features like coffered ceilings, authentic frescoes, timeless marble elements, and a remarkable original marble staircase. Each of the 39 rooms and suites is a testament to the thoughtful preservation of the historical essence of the space that intertwines bespoke contemporary luxury. The hotel’s expansive reception areas and distinctive artwork, and dining can be enjoyed in the sophisticated atmosphere of Core Restaurant and the Palazzo Bar is the place for stylish drinks. All this combined with exemplary service and meticulous attention to detail, offer guests an exclusive retreat in the heart of Rome’s dynamic atmosphere.

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