There are few places as cinematic as Rome. A truly unique city that invites you to channel your main character energy whilst soaking in culture, history, food and drink by the bucket. Many quite rightly flock to the major players – a turn around the Colosseum here, a tour through The Vatican there but make sure you leave time to get lost as the best parts of this city are those you discover when you are least expecting it – bistro table laden baroque piazzas inviting you to sip espresso and watch the world go by, a vibrant and thriving street art scene juxtaposing pops of colour with ancient ruins and food markets full of shouting nonnas and bustling chefs.
No trip to Rome would be complete without retail therapy – from luxury designers to intimate boutiques, days if not weeks can be lost to the art of shopping here. At the end of the day, weary but sated from exploration and absorption, an aperitivo or two at sundown is essential before heading out to revel in one of the city’s hundreds of gastronomic delights.
And as such a desirable destination, Rome is not without its shortage of luxury hotels, from internationally recognised names leading the way in hospitality to independent boutiques enjoying prime locations – and everything in between – the choice is vast. Read on to discover some of our favourite luxury hotels in Rome to help plan your trip.
Pantheon, Rome, Lazio
Orient Express La Minerva
(5 stars) Orient Express La Minerva showcases timeless hospitality with its first ultra-luxury hotel, set within a 17th-century palazzo in the heart of Rome. This landmark property marks a significant debut, for the iconic travel brand, that blends Roman heritage with sophisticated design. Restored by renowned architect and artist Hugo Toro, the interiors channel the elegance of the original Orient Express carriages through rich wood panelling, bespoke travel trunks, hand-painted ceilings, and a palette inspired by Rome’s skies and classical architecture.
Each of the 93 rooms and 36 suites has been individually crafted to reflect the property’s historic soul, with the Stendhal Suite paying tribute to one of the palazzo’s most distinguished former guests. The hotel’s public spaces are equally considered, with a series of lounges and corridors echoing the polished charm of the golden age of travel.
Culinary experiences include La Minerva Bar, set beneath a glass ceiling and flanked by marble columns and the original statue of the goddess Minerva; the Gigi Rigolatto rooftop restaurant, opening in May 2025, promises panoramic views across Rome alongside Riviera-inspired cuisine; and the upcoming Mimi Kakushi, an award-winning pan-Asian concept bringing the creative energy of 1920s Osaka to the Eternal City.
Rome, Lazio
art’otel Rome Piazza Sallustio
(5 stars) art’otel Rome Piazza Sallustio brings a bold, culturally immersive experience to the heart of Rome. Set just steps from the Horti Sallustiani, this contemporary lifestyle hotel comprising 99 stylish rooms, offers guests more than just a stay—it’s a living gallery, with each space enriched by the imaginative works of Signature Artist Pietro Ruffo. His celestial-inspired pieces and Roman iconography feature throughout, creating a striking artistic narrative from lobby to suite.
At the centre of the hotel’s cultural focus is its Art Gallery, which opens with Ruffo’s exhibition Mappare l’Invisibile and forms part of the wider art’beat initiative. This evolving programme brings together visual art, music, fashion, and wellness, offering guests and locals a curated calendar of creative experiences. Culinary artistry also takes centre stage at YEZI, a pan-Asian restaurant led by Executive Chef Werner Seebach and Head Chef Giordano Gianforchetti. With a menu inspired by Asia’s spice routes and a terrace designed by Ruffo himself, YEZI delivers one of the capital’s most imaginative dining experiences.
Central Station, Rome, Lazio
The St. Regis Rome
(5 stars) Known as Rome’s first luxury hotel, has been in business since 1894 when Swiss hotelier, César Ritz, welcomed the first guests. The hotel epitomises world-class accommodation and is situated in the city centre, overlooking one of the city’s most impressive palazzos Piazza della Repubblica. The hotel is conveniently located next to Termini Train Station, as well as the Baths of Diocletian and offers easy access to many of the city’s major landmarks. Old world grandeur blends effortlessly in a sophisticated and distinctive style to bring a contemporary vibe to this historic address. And it’s not just the interiors and amenities that are detailed and intricate, the level of service and attention provided by highly-trained staff is second to none. Guests can enjoy classic Italian and Roman dishes and cocktails and beverages in a relaxed atmosphere at Lumen, the onsite restaurant. The hotel is pet and child friendly. It is clear to see why The St. Regis Rome is regarded as one of the world’s finest hotels.
Rome, Lazio
Rome Cavalieri, A Waldorf Astoria Resort
(5 stars) Offering the most spectacular view over Rome from its elevated position on Monte Mario, the Rome Cavalieri, A Waldorf Astoria Resort will exceed your expectations in so many ways. From its Michelin-star dining room, to its luxury palatial spa and resort style pool, through to its 15 acres of lush parkland and world-class art collection the Rome Cavalieri, A Waldorf Astoria Resort offers an elegant refuge away from the hustle and bustle of the city that will satisfy the most discerning of luxury travellers. At the hotel all rooms are designed with sleeping and living areas and come with a range of stylish features like their indulgent marble bathrooms and spacious balconies for an al fresco breakfast or evening aperitifs. For all-out luxury choose a room on the Imperial floor which includes access to their club lounge and for over the top luxury choose the Planetarium suite which includes masterpieces throughout and a vast private roof terrace and jacuzzi.