Best Luxury Hotels in Italy

ME Milan Il Duca is a unique, contemporary, 5-star escape designed by Aldo Rossi at Porta Garibaldi. The hotel is located in Piazza della Repubblica and close to the iconic Duomo of Milan. There is a range of rooms and suites on offer, including interconnecting options and stunning city views. There are two restaurants serving Italian specialties including the STK Milan Steakhouse. Guests can also enjoy the tranquil Radio Rooftop Bar with its sensational views, sunsets, and cocktail selection. The hotel offers a 24/7 gym facility for guests looking to keep up their fitness regime on the go and is completely pet-friendly. ME Milan Il Duca boasts four sophisticated event spaces, perfect for hosting any function from a business event to a truly unforgettable wedding. The hotel is also part of the MeliáRewards loyalty programme.

The Hoxton, Florence has brought the brand’s distinctive blend of contemporary design and community spirit to the heart of Florence’s historic centre. Following the success of The Hoxton, Rome, this much-anticipated opening spans two contrasting buildings – a beautifully preserved 16th-century Renaissance palazzo and a striking modernist structure by renowned architect Andrea Branzi. The result is a seamless fusion of historic grandeur and bold contemporary style, with interiors by AIME Studios, featuring lime-washed walls, original frescoes, and vintage furnishings.

The hotel offers 161 stylish rooms, with palazzo rooms showcasing elegant marble tones and Renaissance motifs, while Branzi-designed rooms embrace vibrant colours and postmodern influences. For a more exclusive stay, The Hoxton, Florence introduces House, a luxurious three-bedroom apartment with a private entrance, fully equipped kitchen, and terrace, complete with a dedicated House Manager.

Guests can enjoy two exciting dining venues: Alassio, a Mediterranean-inspired restaurant serving classic Italian comfort food with Ligurian influences, and Enoteca Violetta, a sophisticated wine bar offering an extensive selection of local and international wines. Ideally located for exploring Florence’s cultural landmarks, including the Duomo and Uffizi Gallery, the hotel also embraces local collaborations, showcasing emerging Italian artists in the Hox Gallery and offering curated goods in its Best Of shop. Additional perks include complimentary Sergio Bianchi bicycles and exclusive access to local fitness studios, ensuring a stay that’s as immersive as it is stylish.

NH Collection Palermo Palazzo Sitano is housed in an aristocratic Baroque building along Via Vittorio Emanuele, offering 86 rooms and suites that blend original 18th-century features with contemporary touches. Many rooms have cast-iron balconies overlooking the old town, and select Junior Suites feature painted fresco ceilings restored to showcase the palazzo’s artistic heritage. The interiors create a sense of calm and heritage with classic arches, painted ceilings and warm tones softened by modern furnishings.

Dine in the restaurant located within a bright glass structure, where arches and majestic columns evoke the spirit of the neighbouring convent. The menu highlights Sicilian flavours crafted from premium local ingredients with subtle international influences. A welcoming bar opens directly onto Via Bottai, creating a lively link between the hotel and the city.

Facilities include a ground-floor sauna and steam bath, a fitness club with modern cardio equipment, and versatile meeting spaces for small events. Positioned close to Piazza Marina, Porto della Cala and Palermo Cathedral, the hotel places guests within walking distance of cultural landmarks, vibrant markets and boutique shopping

Experience La Dolce Vita in the Eternal City. The new Ambasciatori Palace is InterContinental’s latest lifestyle resort, a grand, early 20th-century building once used to house visiting ambassadors. Found on Via Veneto, it exudes elevated Italian elegance, along with international influences, such as its Scarpetta NYC restaurant. Charlies’ rooftop is the place to hang out long into the night, with live music, DJ sets and mixology along with epic views, plus there’s the Anite Lounge & Bar in the lobby. With accessible rooms, a nanny service, notary services and fitness trainers onsite, this hotel tends to your every need.

While Poetto beach is just minutes away, Palazzo Doglio is very much a city hotel, found in the historic centre of Cagliari. 72 bedrooms are bathed in natural light and feature precious Carrara marble. Created for both business and leisure, there are meetings rooms, a conference theatre and the Doglio Club provides Natura Bissé treatments. Osteria del Forte, a classic trattoria, has the esteemed Executive Chef Alessandro Cocco at the helm. Saudade is the Japanese-Brazilian eatery, Maiori is a contemporary pizzeria, the American Bar serves cocktails and Colonial is the new restaurant concept coming soon.

Another iconic family-run hotel in picturesque Positano is Hotel Marincanto. Having supposedly inspired painters and been used as a movie set Hotel Marincanto has been open since 1967 and offers elegance, privacy and five-star service for guests year round. For those who visit to relax, the infinity pool which blends with the horizon, the exclusive private beach and the ocean-view fitness area will be ideal whilst the Terrazza Cele restaurant offers sophisticated local cuisine on an intimate terrace overlooking the sea. The hotel décor is predominantly cool, muted tones of white or cream, wooden floors, classic furniture, with splashes of colour thanks to vibrant textiles. The owners are hands on with service and the intimate size of the hotel (only 32 rooms) means you can always expect to be treated like a star (even if you aren’t one!). 

A former church (consecrated in 1934), this building now houses 185 guest rooms and suites — some of which have private terraces — in the fashionable CityLife district. The brand blends the property’s old original and ecclesiastical features with the NH group’s signature on-trend new decor and a 13-storey tower wing. On the rooftop, a pool and The District cocktail bar offer panoramic views and a solar power system provides greener energy to the four-star property. And at ground level, there’s an urban garden where you can take breakfast. Lunch and dinner are offered at Tailors restaurant, with a retro, midcentury style.

Nestled near cultural landmarks such as the Guggenheim Collection and Accademia Gallery, Il Palazzo Experimental serves as a hub for both tourists and locals. Its 32 well-appointed rooms and suites are bathed in natural light and offer views of a serene canal and garden. The collaboration between the Experimental Group and the founders of the Italian Supper Club has led to the establishment of Adriatica Restaurant, promising an authentic Italian culinary journey with locally sourced ingredients. The bar, designed by Cristina Celestino, pays homage to Venice through a symphony of marble and antique mirrors, drawing inspiration from Carlo Scarpa.

Nobu Hotel & Restaurant Roma is set along the prestigious Via Veneto, bringing together contemporary Japanese design and timeless Roman elegance in the heart of the Eternal City. The hotel offers 117 rooms and suites, including the striking three-bedroom Nobu Villa with a rooftop terrace overlooking the historic skyline.

Designed by the Rockwell Group, the interiors blend calm minimalism with classic detailing, creating a sanctuary that feels both luxurious and serene. Dining is led by Chef Nobu Matsuhisa, serving his signature Japanese-Peruvian fusion at the main restaurant, alongside an intimate sushi counter and stylish bar.

The hotel also features a serene spa, a state-of-the-art fitness centre, and flexible event spaces. With its prime location close to the Spanish Steps and Villa Borghese, Nobu Hotel Roma embodies sophisticated city living through exceptional design, service, and gastronomy.

Just moments away from the Piazetta, La Scalinatella, is the definition of serenity. La Scalinatella overlooks the sea and cliffs of Capri making it one of Capri’s most beautiful hotels. La Scalinatella’s rooms and suites are bathed in natural light which reflects off the room’s exquisite floor tiles, this makes the rooms feel exceedingly welcoming and comfortable. The hotel is also home to private Villas which offer guests the chance to experience the height of luxury. La Scalinatella is home to all the amenities one might want like a pool on the upper terrace, a second pool overlooking the sea, a fitness centre and a beautifully kept garden. The hotel’s restaurant, Casa Morgano, is a perfect choice for guests wishing to enjoy the incredible culinary traditions of Southern Italy all whilst sitting in one of Capri’s most sophisticated restaurants.

Located on Piazza dell’Unità Italiana, steps from the Duomo, W Florence transforms the former Grand Hotel Majestic into a vibrant, design-led retreat. The hotel offers 119 rooms and suites, including a Penthouse with a 140-square-metre terrace and panoramic city views. Interiors by AvroKO blend 1960s Italian glamour with bold modern details, complemented by artwork from Adam Ellis Studio. Guests can enjoy dining at Tratto, rooftop cocktails at Zefiro (opens late summer 2025), Japanese-Korean cuisine by Michelin-starred chef Akira Back, and social evenings at W Lounge. Additional highlights include a central courtyard, 24-hour FIT gym, rooftop garden, and flexible event spaces.

Housed in a 17th-century residence and named after Count Goffredo Manfredi – one of Rome’s most influential public figures – Palazzo Manfredi is the ultimate luxury getaway in the heart of the city. This five-star boutique hotel is so close to the world’s most famous amphitheatre that you can practically hear the gladiators of old from within your suite. Not only does the hotel offer spectacular views over Rome’s ancient sites, it is only a two-minute walk from Colosseo Metro Station, making travelling to and from the hotel a breeze. Inside, first-class hospitality, elegance and impeccable service combine and are evident throughout its palatial suites and rooms, bar and restaurant including the Michelin Starred Aroma led by Chef Giuseppe Di Iorio. Check in to the Palazzo Manfredi for a truly unforgettable experience. Palazzo Manifred is part of the Small Luxury Hotels of the World group.