
Best Luxury Hotels in Panama City
The capital of the country that links Central and South America, Panama City is a mix of modern and colonial architecture. It’s a jumping-off point for the nearby rainforest, tropical beaches of the adjacent Pacific Ocean and the most famous waterway on earth; the man-made Panama Canal, where metal “mules” pull enormous multi-storey passenger liners and cargo ships through what at first appears to be the most unlikely of narrow spaces (head to the Miraflores Locks for some superb photo ops). Within the city itself, you must be sure to visit Casco Viejo, the fascinating cobblestoned historic quarter, home to a presidential palace.
Panama, Panama City
Hyatt Regency Panama City

Strategically positioned in Panama City’s bustling financial district, Hyatt Regency Panama City offers a seamless blend of business convenience and cultural discovery. The hotel features 382 rooms and suites, each styled with carved wood furnishings and green marble details that reflect Panamanian artistry. Business travellers benefit from work-friendly amenities and access to the Regency Club Lounge, which offers complimentary breakfast and evening hors d’oeuvres. The ground-level pool and 24-hour fitness centre provide welcome relaxation after meetings or city exploration. Guests are just a short drive from cultural highlights like the UNESCO-listed Casco Viejo, the Biodiversity Museum, and the vibrant culinary and nightlife scenes of Panama City.
Dining includes Rulfo, an all-day restaurant that transitions into a lively cervecería, and Amado, a cosy café serving speciality coffees and light bites. Two additional venues, Belisario wine bar and Refugio speakeasy, are set to open in late 2025. With 25,000 sq ft of event space, including a Regency Ballroom, 12 meeting rooms, and an outdoor terrace, the hotel is well-equipped for both corporate functions and celebrations.