Best Luxury Hotels in Pantheon

Discover our favourite luxury accommodation in Pantheon. Our collection of luxury hotels and resorts showcase the very finest in world-class hospitality. Each one has been selected, by our Editors, based on its exceptional service, refined interiors, excellent amenities and standout location. Let our expert selection help you find your perfect place to stay.

Lazio, Rome, Pantheon

Six Senses Rome

Hotel
(5 stars)
At a glance
Rooms 96 rooms and suites, from Junior Suites to one- and two-bedroom Signature Suites, some with private terraces
Amenities BIVIUM all-day restaurant and deli, NOTOS rooftop restaurant, Six Senses Spa with Roman bathing circuit, yoga and fitness classes
More Housed in a restored historic palazzo off Via del Corso, an easy walk from the Trevi Fountain, Pantheon and Colosseum

Marking the brand’s first urban resort, Six Senses Rome brings a wellness-focussed approach to a bustling metropolis. Lashings of interior foliage and planting help create a city-centre oasis that belies its super central location, with celebrated landmarks, such as the Trevi Fountain, Pantheon, and Colosseum all within an easy stroll from the hotel door. Once a bank, the 18th-century Palazzo Salviati Cesi Mellini has been transformed into a stunning five star hotel that offers guests elegant accommodation, supreme wellness and spa facilities, a rooftop terrace and casual dining restaurant – all enhanced with impeccable service.

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Lazio, Rome, Pantheon

Orient Express La Minerva

Hotel
(5 stars)
At a glance
Rooms 93 rooms and 36 suites in a restored 17th-century palazzo, up to the Stendhal Suite
Amenities Gigi Rigolatto rooftop restaurant, La Minerva Bar, Mimi Kakushi, spa
More On Piazza della Minerva in the centro storico, beside the Pantheon and near Piazza Navona

Orient Express La Minerva showcases timeless hospitality with its first ultra-luxury hotel, set within a 17th-century palazzo in the heart of Rome. This landmark property marks a significant debut, for the iconic travel brand, that blends Roman heritage with sophisticated design. Restored by renowned architect and artist Hugo Toro, the interiors channel the elegance of the original Orient Express carriages through rich wood panelling, bespoke travel trunks, hand-painted ceilings, and a palette inspired by Rome’s skies and classical architecture.

Each of the 93 rooms and 36 suites has been individually crafted to reflect the property’s historic soul, with the Stendhal Suite paying tribute to one of the palazzo’s most distinguished former guests. The hotel’s public spaces are equally considered, with a series of lounges and corridors echoing the polished charm of the golden age of travel.

Culinary experiences include La Minerva Bar, set beneath a glass ceiling and flanked by marble columns and the original statue of the goddess Minerva; the Gigi Rigolatto rooftop restaurant, opening in May 2025, promises panoramic views across Rome alongside Riviera-inspired cuisine; and the upcoming Mimi Kakushi, an award-winning pan-Asian concept bringing the creative energy of 1920s Osaka to the Eternal City.

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Lazio, Rome, Pantheon

Radisson Collection Hotel, Roma Antica

Hotel
(5 stars)
At a glance
Rooms 84 rooms and suites in a restored palazzo, up to 80 sqm Friends & Family rooms and Panoramic rooms with terraces
Amenities Modius Roman restaurant, Modius on the Roof rooftop cocktail bar, Turkish bath, Technogym fitness centre
More On Via delle Botteghe Oscure in the centro storico, beside Largo di Torre Argentina and a short walk from the Pantheon

The Radisson Collection has expanded its presence in Italy with the opening of the Radisson Collection Hotel, Roma Antica. This luxurious establishment is located in Rome’s historic centre, close to landmarks like the Altare della Patria and the Pantheon, offering guests a blend of historical charm and modern elegance. Built around the restored Palazzo Lares Permarini, the hotel boasts 89 rooms designed with Carrara marble bathrooms, Fornasetti wallpaper, and refined furnishings. It features panoramic terraces, a Turkish bath, fitness centre, and is pet-friendly. The hotel’s development uncovered archaeological remnants of the Porticus Minucia, which are now accessible to guests, blending Rome’s rich past with a present-day luxury hotel experience. The on-site restaurant, Modius, and the rooftop bar, Modius on the Roof – Terrazza, offer guests a taste of Roman cuisine that uses high-quality, locally sourced ingredients, all enjoyed whilst taking breathtaking city views.

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Radisson Collection Hotel, Roma Antica
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Lazio, Rome, Pantheon

Corso 281

Hotel
(5 stars)
At a glance
Rooms Suites in an 18th-century palazzo, ranging from Studio Deluxe to Executive, Luxury, Romantic and Family Suites.
Amenities Honesty Bar, in-suite chef and private dining, cooking classes, in-suite massage, concierge.
More On Via del Corso in the historic centre, a short walk from Piazza Venezia.

You don’t get any more boutique or high end on Via del Corso than Corso 281 Luxury Suites. Located on the main thoroughfare of the city right in the heart of high street brand shopping, this 12 room property is positioned perfectly. With stunning designer interiors, Nespresso machines, and luxurious Bulgari amenities, each of the architecturally appointed rooms boasts views of Roman rooftops or the grand Piazza Venezia. An added comfort and touch is the smart device in each room to help you navigate the city like a true local.

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Corso 281
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Lazio, Rome, Pantheon

Palazzo Roma

Hotel
(5 stars)
At a glance
Rooms 39 rooms and suites across six categories in a frescoed 17th-century palazzo, up to an Executive Suite
Amenities Core Restaurant for Roman cuisine, Palazzo Bar for cocktails, concierge
More In a 17th-century palazzo on Via del Corso, 100m from both Piazza Venezia and the Trevi Fountain

With an enviable address of Via del Corso, Palazzo Roma, is a historic 16th-century building that has been transformed into a luxurious hotel that fuses modern elegance and historical richness. Once the residence of various noble Tuscan families, this esteemed Roman heritage site now serves as a boutique hotel set across three floors. Its design celebrates the building’s aristocratic past with features like coffered ceilings, authentic frescoes, timeless marble elements, and a remarkable original marble staircase. Each of the 39 rooms and suites is a testament to the thoughtful preservation of the historical essence of the space that intertwines bespoke contemporary luxury. The hotel’s expansive reception areas and distinctive artwork, and dining can be enjoyed in the sophisticated atmosphere of Core Restaurant and the Palazzo Bar is the place for stylish drinks. All this combined with exemplary service and meticulous attention to detail, offer guests an exclusive retreat in the heart of Rome’s dynamic atmosphere.

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